Intermittent Fasting Can Reduce Alzheimer Risk
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The mice were only allowed to eat for six hours each day. In humans, this is equivalent to fasting for 14 hours in each 24-hour cycle – and this appears to help reset the natural circadian rhythm that has been disrupted by Alzheimer's disease.
Changes were also seen down to the molecular level, with some genes associated with disease and inflammation in the brain showing differences in how they were expressed in the fasted Alzheimer's mice.
Implementing a pattern of intermittent fasting is something that can be done relatively easily and quickly – as treatment progresses, it's fairly straightforward.Â
If similar results are found in human trials, this is another promising option to explore in the fight against devastating forms of dementia.
"Anything we can do to help patients restore their circadian rhythms will make a big difference in how we treat Alzheimer's in the clinic and how caregivers help patients manage the disease at home," he said.Â